If efficiency cannot gain inversely proportionate to global crude oil depletion then there is trouble. IMHO there is simply no way efficiency can make the required advances to replace the most energy dense and useful liquid that we've discovered and consume is massive amounts. We have built our infrastructure around the highly inefficient internal combustion engine.

All potentially true, and all completely unrelated to Jevon's Paradox.

While you're right that it'll be almost impossible for efficiency gains to keep up with exponential demand growth in the face of falling production, that has nothing to do with Jevon's Paradox, and invoking it only obscures the very valid point you're trying to make.

Jevon's Paradox is not a general indictment of energy dependency; it's a very narrow observation, and simply doesn't describe most of the problems we're facing.  When it comes to Peak Oil, Jevon's Paradox probably doesn't apply at all.