I remember getting much better gas mileage at high altitude in my BMW on trips across the mountain west.

i didnt notice any real change in gas mileage(at higher altitude), except that i was buying the non ethanol gas. my driving varried, so mileage varried. what i did notice, was that i didnt have as much power as at lower alt.

Alan...I can verify from ancedotal but first hand experience that fuel efficiency while riding a Harley Davidson through 'ethanol country' and fueling up with ethanol fuel results in a minimum mpg drop from 45mpg to 33mpg, or, about 25%. With some ethanol blends from certain stations fuel consumption increased by about 33%. In no case have I ever gotten better fuel mileage with ethanol fuel. I have made the rides on both fuel injected and carburated Harleys and the results have been almost identical. First time riders to the Sturgis Rally and approaching from the South or East have all experienced the reduction in mpg when they reach 'ethanol country'. This is widely known in the biker community and I am surprised that the subject continues to be debated here.

Comment from River, June 4 2008 Drumbeat

If things are well tuned (shouldn't the new electronic controls do this), you should have lower aerodynamic drag at higher altitudes. Also wind can make a large difference.